Osteosarcoma Biology
This information has been written for patients, their families and friends and the general public to help you understand more about how bone cells may become cancerous.
How do bone cells become cancerous (malignant)?
Doctors and scientists do not yet fully understand what causes a normal bone cell to become cancerous. It is known that cells contain important information in their chromosomes called genes, which help them to divide and grow normally. Damage to these genes can cause the cell to behave differently and grow abnormally, which can then lead to development of cancer.
Some people are known to have damage to genes, which can cause them to have an increased risk of developing a cancer, including osteosarcoma. Some examples of this are in the section about 'risk factors for osteosarcoma.'
Doctors and scientists all over the World are involved in research to try to understand the difference between normal bone cells and osteosarcoma cells. This will enable them to find treatments, which can target the abnormal osteosarcoma cells rather than normal cells in the body.
Last reviewed: October 2010; Version: 1.1
Review due: October 2011
The authors and reviewers of this information are committed to producing reliable, accurate and up to date content reflecting the best available research evidence, and best clinical practice. We aim to provide unbiased information free from any commercial conflicts of interest. This article is for information only and should not be used for the diagnosis or treatment of medical conditions. BCRT can answer questions about primary bone cancers, including treatments and research but we are unable to offer specific advice about individual patients. If you are worried about any symptoms please consult your doctor.
