Funded by the Bone Cancer Research Trust

2008 - Click on the titles for a description of the research

Professor Jillian Birch, University of Manchester (£47,555)
A pilot Study of the aetiology and genetics of bone tumours in children, teenagers and young adults.

Professor Nicholas Athanasou and Dr Helen Knowles, University of Oxford (£27,213)
Effect of hypoxia on growth, apoptosis and angiogenic capacity of osteosarcoma and Ewing’s Sarcoma cells: regulation by Hypoxia-inducible Factor.

Professor Josef Vormoor, Northern Institute for Cancer Research, Newcastle University (£31,772)
Molecular mechanisms of organ-specific Ewing’s sarcoma metastasis.

Dr Richard McNally, Newcastle University (£30,601)
Environmental contributions to the aetiology of bone tumours in young people: small area analyses.

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2007 - Click on the titles for a description of the research

Professor Adrienne Flanagan, Royal National Orthopaedic Hospital, Middlesex (£28,800)
Cancer stem cells in Osteosarcoma: potential for development of new prognostic markers and treatment.

Dr Agamemnon Grigoriadis, King’s College, London (£29,720)
Identifying a novel role for deregulated Fibroblast Growth Factor Receptor signalling in the growth control of human Osteosarcoma cells.

Dr Rachael Windsor, University College Hospital, London (£30,000)
A pilot pharmacogenomic study of the influence of cytotoxic metabolising gene polymorphisms on toxicity and outcome in resectable Osteosarcoma.

26 & 27th March 2007, Belfry Hotel, West Midlands
International Consensus Meeting on Local Control of Ewing’s Sarcoma.

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2006 - Click on the titles for a description of the research

Dr Richard McNally, Newcastle University (£29,985)
An epidemiological study of bone tumours in children and young adults.

Dr John Anderson, Unit of Molecular Haematology and Cancer Biology,
Institute of Child Health, London (£34,500)
Development of clinical protocols for Ewing’s Sarcoma treatment using gene transfer of T cell receptors.

Funded by the Adam Dealey Foundation

Fifth Round 2005 in conjunction with Patricia Smith

6) Dr Sue Burchill, University of Leeds (£24,516) - "Exploiting hypoxia and angiogenesis for therapeutic advantage in Ewing's Sarcoma family of tumours"

7) Dr Jeremy Whelan University College London Hospitals (£25,0000) - "Two clinical trials of treosulfan in relapsed and advanced Ewing's Sarcoma"

Fourth Round 2004

5) Dr Ian Lewis St James's University Hospital Leeds (£25,000) - "Developing a methodology to investigate international differences in presentation and outcome in patients with Ewing's Sarcoma"

Third Round 2002

4) Prof Chris Boshoff/ Dr Richard Frow The Wolfson Institute (£20,000) "RNA interference as a novel therapeutic tool against Ewing's Sarcoma/Primitive Neuroectodermal Tumours"

Second Round 2000

3) Dr Sue Burchill, University of Leeds (£33,377) - "The role of novel FGFr3 variant in the development an behaviour of Ewing's Sarcoma"

First Round 1998

1) Dr Sue Burchill, University of Leeds (£20,992) - "Basic fibroblast growth factor (bFGF)-induced apoptosis and fibroblast growth factor receptor (FGFr) expression in Ewing's Sarcoma"

2) Dr Nick Coleman, University of Cambridge (£10,000) - "Assessment of chromosomal abnormalities I Ewing's / PNET tumours by 24 colour FISH, colour banding and comparative genomic hybridisation"