Full Title: A Randomised, Single Blind Study Assessing Radiological Outcomes for Massive Segmental Femoral Replacements Using Either Porous Collar or Porous Collar With HA or Porous Collar With HA and Autologous Stem Cells

Status: Active, Recruiting

Age Range: 18 years and older


Royal National Orthopaedic Hospital NHS Trust, London

Registry Number: NCT03905174

This clinical trial aims to assess how effective custom-made prosthetic implants are for bone cancer patients.

The current surgical treatment of many bone cancer patients and revision limb salvage requires the use of endoprosthetic bone implants.

The incidence of aseptic loosening is a major cause of prosthesis failure in these patients; this trial aims to explore ways to reduce such failures and will would allow extending the longevity of implants, particularly for the young population.

Hydroxyapatite (HA) is a naturally occurring calcium mineral that has been used for bone repair and substitution. This study will review the use of implants in the femur, coated with and without HA, and the patients' own stem cells.

If you would like any more information on clinical trials in general, please contact us at The Bone Cancer Research Trust. For more information on this trial and to understand if you are eligible, please talk to your clinical team.

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