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Is friendly bacteria the way to target osteosaroma cells?
Using bacteria to deliver treatment directly to the tumour.
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Is there an association between fluoride levels in drinking water and bone cancer incidence?
Drinking water and the incidence of bone tumours
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Development of a targeted methotrexate prodrug with enhanced therapeutic index for osteosarcoma
Making methotrexate a kinder and more effective treatment for patients.
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ICONIC
ICONIC – Improving Outcomes through Collaboration In Osteosarcoma
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Validation of DNA methylation-specific markers for circulating tumour DNA analysis in sarcoma patients
Can we develop blood tests to help patients?
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Novel tissue engineering technology to facilitate Osteosarcoma Research
Bone-in-culture as an orthotopic platform for the study of patient-near tumour grafts…
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Targeting the Hippo Pathway for Osteosarcoma Therapy
This 'Strictly Research 2017' project looks at the effects of tumour pressure
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Improving the science behind personalised medicine
Aiming to predict the effects of therapeutic methods with increased accuracy
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A study of bone tumours in children and young adults
Identifying trends in bone tumour incidence..
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Can your genetic ‘make-up’ change the way you respond to chemotherapy?
Dr Rachael Windsor studies patients response to chemotherapy drugs...
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A pilot-study regarding the cause of osteosarcoma and Ewing sarcoma
Taking steps to investigate the cause of primary bone tumours...
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Can bisphosphonates be used in the treatment of osteosarcoma?
Zolendronic Acid and the treatment of osteosarcoma...
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Creating 3D models to induce tumour cell death
3D models of cells may selectively kill tumour cells..
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International Osteosarcoma Research Symposium 2019
Moving osteosarcoma research forward.
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A Potential New Therapeutic Target in Osteosarcoma
Investigating ANGPTL4 role in osteosarcoma progression
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Evaluating a Diagnostic and Therapeutic Molecule in Ewing sarcoma and Osteosarcoma
Tackling key areas to work towards improving patient response to treatment.
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Characterising Osteosarcoma's Microenvironment
Characterising the tumours microenvironment to improve treatment strategies.
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Identifying biological treatment targets in osteosarcoma
Screening osteosarcoma cell lines in order to identify therapeutic targets
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Determining the function and possible targeting of NG2/CSPG4 in osteosarcoma
Investigating a novel target to prevent the metastasis of osteosarcoma.
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Improving patients' quality-of-life and long term outlook
Investigating the function of a regulatory protein in osteosarcoma
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The establishment of an osteosarcoma disease model
Developing cell lines to enhance findings and pin-point genetic abnormalities of osteosarcoma
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Uncovering FGFR: a complex yet potential treatment target
Can FGFR be targeted to treat ostesarcoma?
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Searching for the ‘Achilles Heel’ of primary bone cancer
Investigating a novel target to treat bone cancer...
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Overcoming Resistance to Chemotherapy in Osteosarcoma
Our 'Strictly Research 2017' winner investigates an obstacle in treating osteosarcoma...
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Putting radiotherapy advances into action for primary bone cancer
Assessing the use of advanced radiotherapy techniques in the treatment of primary bone…
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TP53 restoration using mRNA vaccine technology
TP53 restoration using mRNA vaccine technology
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Hypoxic extracellular vesicles in osteosarcoma lung metastasis
Delineating the role of hypoxic extracellular vesicles in pulmonary metastasis of osteosarcoma…
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Bone-seeking metal based drugs to treat chemotherapy resistant osteosarcoma
Bone-seeking metal based drugs to overcome chemotherapy resistant osteosarcoma sub-populations
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Developing novel biomaterials for osteosarcoma and chordoma treatment
Developing novel biomaterials for osteosarcoma and chordoma treatment
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Further exploration of a potential novel therapeutic target in osteosarcoma
Further exploration of ANGPTL4 as a potential therapeutic target in osteosarcoma
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Unravelling the diversity of bone tumours: investigating the differences between single cancer cells.
Unravelling the diversity of bone tumours
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Haem oxygenase-1 (HO-1), a novel druggable target for prevention of osteosarcoma growth and metastasis
By inhibiting HO-1 can we block osteosarcoma development and metastasis?
Completed Research Projects
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