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Characterising Osteosarcoma's Microenvironment
Characterising the tumours microenvironment to improve treatment strategies.
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Determining the function and possible targeting of NG2/CSPG4 in osteosarcoma
Investigating a novel target to prevent the metastasis of osteosarcoma.
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Demonstrating a novel target for osteosarcoma treatment
Investigating P2X7R in osteosarcoma growth and behaviour
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E-learning module for GPs
We have partnered with The Royal College of GP's to aid an earlier diagnosis of primary…
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Identifying biological treatment targets in osteosarcoma
Screening osteosarcoma cell lines in order to identify therapeutic targets
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Identifying key drivers of chondrosarcoma
Predicting the behaviour of chondrosarcoma
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Could this be the first ever clinical biomarker for chondrosarcoma?
Improving diagnostic methods and treatment planning in chondrosarcoma
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Preventing the Growth and Spread of Osteosarcoma
Investigated a promising treatment target for osteosarcoma spread and growth
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Overcoming Resistance to Chemotherapy in Osteosarcoma
Our 'Strictly Research 2017' winner investigates an obstacle in treating osteosarcoma...
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Targeting the Hippo Pathway for Osteosarcoma Therapy
This 'Strictly Research 2017' project looks at the effects of tumour pressure
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Improving patients' quality-of-life and long term outlook
Investigating the function of a regulatory protein in osteosarcoma
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Identifying patients with a higher risk of tumour recurrence
Creating better designed treatment plans for Ewing sarcoma patients
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Improving the science behind personalised medicine
Aiming to predict the effects of therapeutic methods with increased accuracy
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Oncolytic virus therapy for Ewing sarcoma
Exploiting the body's own immune system to fight Ewing sarcoma
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Modelling Ewing sarcoma heterogeneity and tumour microenvironment to improve outcomes
Creating a unique preclinical tool combining Ewing sarcoma and tumour microenvironment…
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Improving the success rate of surgery for osteosarcoma patients
Using advanced imaging to improve the planning of surgery
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National Ewing Sarcoma Multidisciplinary Team Meeting
Collating data from previous NEMDT meetings to improve the systems and treatment of Ewing…
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Putting radiotherapy advances into action for primary bone cancer
Assessing the use of advanced radiotherapy techniques in the treatment of primary bone…
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Sarcoma Awareness for Junior Doctors
Supporting the awareness of sarcoma, and its care, for junior doctors
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Evaluating a Diagnostic and Therapuetic Molecule in Ewing sarcoma and Osteosarcoma
Tackling key areas to work towards improving patient response to treatment.
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A Potential New Therapeutic Target in Osteosarcoma
Investigating ANGPTL4 role in osteosarcoma progression
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Using Imaging Scans after Chemotherapy to Improve Surgical Planning
Assessing the effectivness of Ewing sarcoma surgical procedures
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Exploring Patient Experiences
Investigating and improving the care primary bone cancer patients receive
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Collecting patient samples for research
Oxford Sample Collection Infrastructure Grant
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Collecting patient samples for research - Birmingham
Birmingham Sample Collection Infrastructure Grant
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Development of a targeted methotrexate prodrug with enhanced therapeutic index for osteosarcoma
Making methotrexate a kinder and more effective treatment for patients.
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ICONIC
ICONIC – Improving Outcomes through Collaboration In Osteosarcoma
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Therapeutic targeting and understanding of oncogenic driver networks in chordoma
Finding targets to develop new treatments for chordoma.
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Haem oxygenase-1 (HO-1), a novel druggable target for prevention of osteosarcoma growth and metastasis
By inhibiting HO-1 can we block osteosarcoma development and metastasis?
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Validation of DNA methylation-specific markers for circulating tumour DNA analysis in sarcoma patients
Can we develop blood tests to help patients?
Current Research Projects
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