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Current Research Projects

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  • All cancer types
  • Adamantinoma
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  • Could this be the first ever clinical biomarker for chondrosarcoma?

    Improving diagnostic methods and treatment planning in chondrosarcoma

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  • Preventing the Growth and Spread of Osteosarcoma

    Investigated a promising treatment target for osteosarcoma spread and growth

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  • Oncolytic virus therapy for Ewing sarcoma

    Exploiting the body's own immune system to fight Ewing sarcoma

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  • Sarcoma Awareness for Junior Doctors

    Supporting the awareness of sarcoma, and its care, for junior doctors

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  • Collecting patient samples for research

    Oxford Sample Collection Infrastructure Grant

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  • Collecting patient samples for research - Birmingham

    Birmingham Sample Collection Infrastructure Grant

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  • Development of a targeted methotrexate prodrug with enhanced therapeutic index for osteosarcoma

    Making methotrexate a kinder and more effective treatment for patients.

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  • ICONIC

    ICONIC – Improving Outcomes through Collaboration In Osteosarcoma

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  • Therapeutic targeting and understanding of oncogenic driver networks in chordoma

    Finding targets to develop new treatments for chordoma.

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  • Haem oxygenase-1 (HO-1), a novel druggable target for prevention of osteosarcoma growth and metastasis

    By inhibiting HO-1 can we block osteosarcoma development and metastasis?

    Read more
  • Validation of DNA methylation-specific markers for circulating tumour DNA analysis in sarcoma patients

    Can we develop blood tests to help patients?

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  • Identification and investigation of a novel gene implicated in treatment resistant Ewing sarcoma

    Read more
  • Identifying key drivers of chondrosarcoma

    Predicting the behaviour of chondrosarcoma

    Read more
  • Novel tissue engineering technology to facilitate Osteosarcoma Research

    Bone-in-culture as an orthotopic platform for the study of patient-near tumour grafts…

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  • Understanding the Evolutionary Processes of Metastatic Chondrosarcoma

    Posthumous evaluation of a high-grade widely disseminated chondrosarcoma though analysis…

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  • Investigating the potential of signalling proteins to monitor and treat adamantinoma relapse and spread

    Targeting the MEK5-ERK5 pathway: a novel approach to treat Adamantinoma?

    Read more
  • Identification of novel biomarkers for the management of adamantinoma

    Novel markers for diagnosis, monitoring and potential treatment of adamantinoma

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  • Novel cell surface protein inhibitors for treatment of Ewing sarcoma

    Novel CD99 inhibitors for treatment of Ewing sarcoma

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  • Does oestrogen have a protective effect in chondrosarcoma?

    The Role of Oestrogen in Chondrosarcoma Using Patient-Derived Xenograft Models: A Pilot…

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Bone Cancer Research Trust - Until There's a Cure

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