Current Research Projects

New ways to help the immune system fight osteosarcoma:

Novel strategies to overcome immunosuppression in the tumour microenvironment

Enabling early diagnosis of osteosarcoma – the SPEED study

Stopping the alpha - a potential new treatment approach for osteosarcoma

Mimicking the journey through the bloodstream: exploring how osteosarcoma cells spread and survive elsewhere in the body

Novel immunotherapy approach against osteosarcoma

Overcoming osteosarcoma immunotherapy resistance through a novel, IL-12 driven approach

Advancing the ICONIC trial: Improving outcomes through Collaboration in Osteosarcoma

Advancing the ICONIC trial: Improving outcomes through Collaboration in Osteosarcoma

Towards precision medicine in Osteosarcoma

Developing genome-informed treatment to improve outcome in Osteosarcoma

Kinder drugs to treat osteosarcoma

Optimisation of tumour-targeted methotrexate prodrugs for osteosarcoma

Understanding osteosarcoma chemotherapy resistance

Cellular Dynamics of Chemotherapy Resistance in Osteosarcoma

Searching for new drugs to treat osteosarcoma

Preclinical validation of novel compounds to treat osteosarcoma

Developing an effective CAR T cell therapy for osteosarcoma

Towards Engineered T Cells for Osteosarcoma

Sensitising osteosarcoma to immunotherapy

Modulation of interferon gamma-mediated signalling and immune response by fibroblast growth…