Current Research Projects

Engineering a laboratory tool to identify safer and more effective immunotherapies against Ewing sarcoma

Preclinical selection of STEAP1-targeting bispecific antibodies for Ewing Sarcoma using…

Developing TCR-T immunotherapy for the treatment of Ewing sarcoma

Developing TCR-T immunotherapy for the treatment of Ewing sarcoma

A data programme to transform patient care

ASPIRE: A Sarcoma data Partnership to Improve patient outcome and Reduce inEqualities

Brachyury targeting in chordoma

Evaluating the therapeutic potential of a new approach to targeting brachyury in human…

Harnessing the immune system to treat Ewing sarcoma in the lungs

Harnessing the immune system to treat Ewing sarcoma in the lungs

A multi-faceted investigation of chondrosarcoma biology to inform targeted treatment

A multi-faceted investigation of chondrosarcoma biology to inform targeted treatment

Enabling early diagnosis of osteosarcoma – the SPEED study

DIAGNOSED: Data-driven Integrated Approach to Generate Novel Opportunities for Sarcoma…

Mimicking the journey through the bloodstream: exploring how osteosarcoma cells spread and survive elsewhere in the body

Investigating individual cells to understand the key genetic changes leading to mesenchymal chondrosarcoma

Looking at the HEY1-NCOA2 fusion gene in mesenchymal chondrosarcoma as a potential target…

Novel immunotherapy approach against osteosarcoma

Overcoming osteosarcoma immunotherapy resistance through a novel, IL-12 driven approach

The impact of spine sarcoma on psychological wellbeing: an exploratory study

The impact of spine sarcoma on patient wellbeing

Identifying biomarkers for treatment response in Ewing sarcoma

Optimising the treatment of Teenagers and Young Adults with Ewing sarcoma through an increased…

Advancing the ICONIC trial: Improving outcomes through Collaboration in Osteosarcoma

Advancing the ICONIC trial: Improving outcomes through Collaboration in Osteosarcoma

Towards precision medicine in Osteosarcoma

Developing genome-informed treatment to improve outcome in Osteosarcoma

Developing an effective CAR T cell therapy for osteosarcoma

Towards Engineered T Cells for Osteosarcoma

Sensitising osteosarcoma to immunotherapy

Modulation of interferon gamma-mediated signalling and immune response by fibroblast growth…