​Since the Bone Cancer Research Trust was formed in 2006, we have awarded over £8.7 million to research focused on improving outcomes for primary bone cancer patients. To date, we have funded 165 research grants and continue to expand our research network, encouraging more researchers to focus their expertise on primary bone cancer.

Open funding calls

Collaborative funding for Ewing sarcoma and osteosarcoma

The Bone Cancer Research Trust is delighted to be partnering with Children’s Cancer and Leukaemia Group (CCLG) to fund research focused on Ewing sarcoma and osteosarcoma.

Over the past several decades, advancements in the treatment of Ewing sarcoma and osteosarcoma have remained limited; both involve intensive and toxic chemotherapy regimens, with patients facing grueling immediate, longer term and late effects of treatment, as well as the risk of relapse and recurrence. Methods of determining prognosis and predicting or monitoring response to treatment are also lacking.

Both charities are committed to improving outcomes for patients and believe the best way to do this is to fund high impact, collaborative research.

Ewing sarcoma funding

BCRT and CCLG are keen to support both basic science and translational proposals that demonstrate a clear line of sight to patient benefit, irrespective of how far from clinical application the project is. We are particularly interested in applications focusing on the discovery, development or validation of biomarkers of Ewing sarcoma. Biomarkers may be prognostic, predictive or markers of response and may be patient sample derived or imaging biomarkers.

Funding is available to support Idea grants and Project grants.

Idea or pilot grants should be focused on gaining preliminary data and show a clear path to larger funding applications. These are usually capped at £35,000, however, this may be increased to £50,000 in exceptional cases. Applicants should contact us to discuss this prior to submitting an application.

Funding for Project Grants is usually capped at £250,000, however, we would recommend applicants contact us to discuss proposals seeking funding over this value. These applications must be evidence based and demonstrate a clear trajectory, irrespective of timescales, towards clinical implementation.

Funding is available to both UK and international applicants based in an academic or clinical institution. Please note, international applicants can act as Principal Investigators but must ensure that they include a Co-Applicant or Collaborator based at a UK institution in their application.

Osteosarcoma funding

Funding is available to support Idea (pilot) grants, which should be focused on gaining preliminary data and show a clear path to larger funding applications. These are usually capped at £35,000, however, this may be increased to £50,000 in exceptional cases. pplicants should contact us to discuss this prior to submitting an application. Funding is available to applicants based at a UK academic or clinical institution.

Projects should be hypothesis generating and should be focused on accelerating progress in osteosarcoma research. Projects may be discovery focused or translational, however, must demonstrate thought to patient benefit or clinical application, irrespective of timescales.

Patient & Public Involvement in the development of applications will be expected. The Bone Cancer Research Trust has a Patient and Public Involvement Panel (PPIP), who may be contacted to support your application. Please email us to find out more about how to engage with the panel.

All costings will be fully scrutinised and so clear justifications should be included.

The closing date for this funding scheme is 5pm on Friday 24th May 2024 and awards are likely to be made in Q4 2024.

To request an application, please contact us here.

Improving Sarcoma Diagnosis Funding Call

The Bone Cancer Research Trust and Sarcoma UK are delighted to be working together on this funding call, focussed on research to improve diagnosis for people affected by sarcoma.

Sarcomas are challenging to diagnose. They can affect anyone, occur anywhere in the body, and have over 100 subtypes, with a diverse range of symptoms. But with low case numbers, awareness is poor. These and many other factors contribute to lengthy waits for patients to get the correct sarcoma diagnosis. 1 in 3 sarcoma patients wait at least 6 months from first presenting with symptoms, and it takes bone sarcoma patients an average of 8 visits to a healthcare professional to receive their diagnosis.

In prioritisation exercises carried out by both charities, research into improving diagnosis is a close second priority behind research into new and better treatments for people affected by sarcoma. However, this is a challenging area in terms of developing research proposals which fit the diverse needs of the patient community.

This Improving Sarcoma Diagnosis funding round aims to fund scientific and clinical research projects which ultimately aim to drive positive change in how sarcomas are detected and diagnosed. Proposals must have a clear and considered line of sight towards improving the diagnosis for sarcoma.

The budget for this funding call is £500,000 for research projects applicable to all types of sarcoma or bone sarcoma only. Available grant sizes include:

  • Small grants: innovative pilot projects or requests to support small pieces of follow-on research needed to complete a project up to a maximum value of £100,000.
  • Large grants: substantive pieces of research supporting a member of staff up to a maximum value of £250,000.

Please note that PhD studentships are not offered through this funding calI.

Key dates:

Call opens: February 2024

Deadline for submissions: Applications must be submitted to research@sarcoma.org.uk by 12pm midday (BST) Thursday 20th June 2024. Applications received after this deadline will not be accepted.

Applicant response to peer and lay review: October 2024

Applicants informed of outcome: December 2024

Completed applications should be sent to research@sarcoma.org.uk

For more information on this this funding call, please contact research@sarcoma.org.uk or research@bcrt.org.uk.

Application and guidance forms can be obtained here

Skill development grants

Through this funding scheme, the Bone Cancer research Trust helps UK based primary bone cancer researchers, at all levels in their careers, to travel nationally or internationally, to present their results at internationally recognised research conferences, whilst interacting with other researchers and establishing networks of collaboration.

The funding also enables researchers to travel to international or national laboratories, to carry out a research project or develop a specific skill that can then be applied at their institution of origin.

ELIGIBILITY

All primary bone cancer researchers based at a recognised UK institution. There are no limitations based on career development stage, but applications from early career researchers are particularly encouraged.

WHAT IS FUNDED

Funding for each application is limited to £3000 and should be in line with distance of travel and length of stay.

  • Conference attendance: funding will cover registration, accommodation and travel costs.
  • Laboratory stays: funding will cover travel, accommodation and research expenses to visit a collaborating research group.

This is a rolling scheme; applications may be submitted at any point and will be considered by the Skills Development Grants committee at BCRT.

More details can be found here.

To obtain an application form, please contact us.

Clinical Trials Support Scheme

The Bone Cancer Research Trust are committed to improving outcomes for patients with primary bone cancer and believe the best way to do this is to fund high impact, collaborative research. We are keen to support all stages of research, from pilot projects, through to more substantive research and have developed this funding call to meet these needs.

Funding of up to £100,000 is available to provide additional support ongoing clinical trials. The trial may be observational or interventional and can be oncology or surgical. This additional funding may be used to support:

  • aligned biological studies
  • additional arms or research questions (observational or interventional)
  • toxicology studies

A small proportion of the grant may also be used to support infrastructure costs.

The funding is available for UK applicants and the proposed research or study must take place in the UK; however, the parent clinical trial may be taking place in the UK or internationally.

Proposals should clearly describe the funded trial, including the value of the funding already secured, start date and duration of the funding award and details on data sharing, IP and T&Cs. The proposal should describe the background evidence, including figures and previous publications, that have been used to support the submitted project, how the described design will answer the questions posed in the proposal and how the additional support will give added value to the current trial. The input from patients on the design and development of the proposal should also be described.

Costings submitted will be fully scrutinised and so applicants should fully justify all costs included.

This is a rolling scheme, applications may be submitted at any point and will be considered at the next available meeting of BCRT's Independent Scientific Advisory Panel.

To discuss the scope of this scheme or the possibility of applying for funding over £100,000 and to obtain an application form, please contact us.


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